Recent progress on the application of biosensors in biomechanics for the early detection of infectious diseases
Abstract
Infectious diseases continue to pose a significant threat to global and public health, particularly in regions with limited access to well-equipped medical facilities. This project focuses on the application of biosensors in biomechanics for the early detection of infectious diseases. Biosensors are analytical devices used to detect various biomolecules, such as bacteria, viruses, and protein biomarkers. To enhance their effectiveness in integrated diagnostics, it is crucial to develop biosensors that are both rapid and highly sensitive. This research explores the potential of biosensors in biomechanics for the early identification of infectious diseases, with a focus on their design, functional mechanisms, and overall efficacy. Biosensors can be integrated with biomechanical principles to enhance their detection performance and range of use. For example, piezoelectric crystal biosensors can convert mechanical vibrations or pressure changes into electrical signals, enabling the detection of biomolecules when they interact with the sensor surface. Additionally, biosensors can be used to detect the mechanical properties of cells, such as cell stiffness and adhesion forces, which are significant for studying cell states and disease progression. The results suggest that biosensors present a viable option for early diagnosis, offering reliable, rapid, and cost-efficient alternatives to traditional diagnostic methods. The development of quick, highly sensitive biosensors could bridge the gap in early detection of infectious diseases, providing timely interventions that could reduce the spread and impact of such diseases. Furthermore, the integration of biosensors with biomechanical principles can lead to innovative diagnostic tools that not only detect the presence of pathogens but also provide insights into the mechanical changes associated with disease progression.
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