Global trends of bone marrow mesenchymal stem cells in tissue engineering: A bibliometric analysis

  • Xiaoying Wang College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Hongyu Chen Air Force Medical Center, Air Force Medical University, Beijing 100142, China; Clinical College of Air Force Medical Center, Anhui Medical University, Beijing 100142, China
  • Mengnan Xu Air Force Medical Center, Air Force Medical University, Beijing 100142, China; Graduate School, China Medical University, Shenyang 110122, China
  • Zihan Huang Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Tao Sun Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Lei Wang Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Bairong Li Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Yujie Yan College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Xiuping Jia College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Danhe Sun College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China
  • Shoubin Ning College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China; Clinical College of Air Force Medical Center, Anhui Medical University, Beijing 100142, China
  • Chongxi Fan College of Life Science, Northwest University, Xi’an 710069, China; Air Force Medical Center, Air Force Medical University, Beijing 100142, China; Clinical College of Air Force Medical Center, Anhui Medical University, Beijing 100142, China
DOI: https://doi.org/10.62617/mcb1272
Keywords: bone marrow mesenchymal stem cells; tissue engineering; bibliometrics; CiteSpace; VOSviewer
Article ID: 1272

Abstract

Bone marrow mesenchymal stem cells (BMSCs) tissue engineering has been an emerging field of research in recent years. Given the increasing global interest, we utilized a bibliometric analysis and visualization of studies on BMSCs in the field of tissue engineering published from 2004 to 2023 to explore research progress and identify future research directions. Data was collected from the Web of Science Core Collection (WoSCC), and in-depth analysis was conducted using various bibliometric tools, including CiteSpace, VOSviewer, and R-Bibliometrix. Our study revealed the historical development and evolution of active topics in BMSCs in terms of temporal dynamics, covering 2967 publications, 65 countries, 2454 academic institutions, and 605 journals, with significant growth observed over the last 20 years. China and the United States dominate the global research landscape. Shanghai Jiao Tong University is one of the most significant contributors to the field. In terms of co-citation analysis, Biomaterials was identified as a key journal. Our analysis also revealed current trends such as extracellular vesicles, exosomes, 3D printing, hydrogels, and nanomaterials. These findings provide a clear perspective for future research on the tissue engineering of BMSCs. This study fills a gap in the field of bibliometrics, enabling researchers to identify popular research areas and providing a comprehensive perspective and broad outlook on this emerging field of research.

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Published
2025-02-28
How to Cite
Wang, X., Chen, H., Xu, M., Huang, Z., Sun, T., Wang, L., Li, B., Yan, Y., Jia, X., Sun, D., Ning, S., & Fan, C. (2025). Global trends of bone marrow mesenchymal stem cells in tissue engineering: A bibliometric analysis. Molecular & Cellular Biomechanics, 22(4), 1272. https://doi.org/10.62617/mcb1272
Issue
Vol. 22 No. 4 (2025)
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Article

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