Deadline for manuscript submissions: 31 March 2026

 

Special Issue Editors

 

Dr. Haocai Chang Website  E-Mail: changhc@scnu.edu.cn
Guest Editor
College of Biophotonics, South China Normal University, China
Interests: Non-invasive Brain Function Modulation

 

Dr. Qi Shen Website  E-Mail: shenqi@scnu.edu.cn
Guest Editor
College of Biophotonics, South China Normal University, China
Interests:Photobiomodulation for Brain Neuromodulation

 

 

Special Issue Information

 

This special issue explores how mechanical forces shape brain function and how we can harness this knowledge for therapeutic breakthroughs. We examine the fundamental ways physical stimuli - from subtle cellular pressures to targeted ultrasound waves - influence neural networks and behavior.

 

Key aspects include: Nature's Blueprint - How the brain naturally uses mechanical signals in learning, memory, and adaptation Engineering Solutions - Innovative technologies that apply precise physical forces to modulate brain activity Clinical Translation - Developing treatments for neurological disorders by correcting abnormal mechanical signaling.

 

The collection bridges three critical scales: Molecular: Mechanics of ion channels and cellular structures Circuit: How forces influence network communication System: Whole-brain mechanical properties and function.

 

We highlight both the tremendous potential and important challenges of this emerging approach, from ensuring treatment precision to addressing ethical considerations in neurotechnology development.

 

 

Keywords:

• Brain modulation technology
• Neural circuit remodeling
• Neurodegenerative diseases
• Mechanotransduction

 

 

 

Published Papers