Deadline for manuscript submissions: 31 August 2025

 

Special Issue Editors

Dr. Silvia Radrezza  Website  E-Mail: radrezza@mpi-cbg.de
Guest Editor
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Interests: clinical and spatial lipidomics through high resolution shotgun mass spectrometry

 

Special Issue Information

Dear colleagues,

 

In the last decades, the field of lipidomics has significantly advanced, driven by technological innovations and a growing appreciation of the importance of lipids in health and disease.

 

The evolution of high-throughput technologies, mainly in the field of mass spectrometry, contributed to a significant enhancement of lipid profiling through a simultaneous detection of several lipid classes and, as consequence, more comprehensive analyses of lipid composition and functionality. Understanding the mechanisms under lipid synthesis, degradation, and remodeling brought us to the discovery of their potential role in diseases like metabolic disorders, cancer, etc. Not only. Thanks to advanced approaches, we are now able to point out potential biomarkers for a specific condition like metabolic dysfunction-associated steatotic liver disease or MASLD (previous non-alcoholic fatty liver disease, or NAFLD), proving the impact of lipidomics in the clinic. Lipidomics profiling can also inform drug development by providing lipid targets for innovative interventions. Moreover, ad hoc bioinformatics analyses integrate lipidomics and other "omics sciences” paving the way for personalized medicine approaches. In fact, a growing awareness of the inter-variability will provide new and tailored therapeutic strategies improving the patient's outcome.

 

This special issue wants to highlight the variety of new lipidomics’ applications, focusing on its relevance in metabolic regulation, diagnostics, therapeutic and technological innovations.

 

We welcome a diversity of articles, such as conceptual and empirical articles, reviews, critical comments, and meta-analyses, for submission to this Special Issue. We will accept manuscripts from different disciplines, addressing topics related to the scope.

 

Dr. Silvia Radrezza

Guest Editor

 

Keywords

lipidomics
technological innovations in lipidomics
metabolic regulation
diagnostic and therapeutic strategies
lipid biomarkers
discovery
personalized medicine
biomedical research

 

Published Papers